![]() ![]() ![]() Many causes of cardiomyopathy in children are related to genetic abnormalities - rather than Type 2 diabetes, alcoholism, long-term high blood pressure or family history, as seen in adults. So, treatments in children, which may range from replacing missing enzymes to heart transplantation, must be tailored to the root causes of their cardiomyopathy.” ![]() “Children don’t have the same behavioral or environmental factors contributing to cardiomyopathy - in general, they don’t smoke they don’t drink alcohol they don’t have long-standing conditions such as obesity or Type 2 diabetes. “Children’s cardiomyopathies may have similar names to cardiomyopathies in adults however, they often have very different causes, different risk factors, different paths of progression and different outcomes,” Lipshultz explains. The statement emphasizes important differences among treatment types for cardiomyopathies and heart failure in children and adults. His work includes development of the National Heart, Lung, and Blood Institute-funded Pediatric Cardiomyopathy Registry, which led to the first improvement in clinical outcomes of medical management for the condition in decades. Lipshultz has been continuously funded by the National Institutes of Health to conduct research on pediatric cardiomyopathies for nearly four decades. Lipshultz, professor of pediatrics in the Jacobs School of Medicine and Biomedical Sciences at UB, chaired the writing group that developed the statement, a companion to the association’s 2019 scientific statement focused on diagnosing the condition, an effort that Lipshultz also chaired. Published June 8 in Circulation, the statement notes there are several types of cardiomyopathies in children and treatment should be personalized based on the cause, symptoms and progression of the condition in each child. Pediatric cardiomyopathies affect 1 of every 100,000 children, according to population-based studies in the United States, Finland and Australia. The American Heart Association has issued its first scientific treatment statement for pediatric cardiomyopathy, a rare disorder affecting the structure of the heart muscle that can lead to heart failure and death. ![]()
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